Isolation and Characterization of Protease Inhibitors from Animal Tissues

نویسندگان

  • Tzi Bun Ng
  • Randy Chi Fai Cheung
  • Jack Ho Wong
  • Xiu Juan Ye
چکیده

The intent of this article is to review protease inhibitors produced from a diversity of animals including cnidarians, annelids, insects, crustaceans, mollusks, fish, amphibians, reptiles and mammals. They can be isolated from various tissues including pancreas, ova, liver, seminal plasma, serum, venom, skin secretion, hemolymph and salivary glands. Animal protease inhibitors display a variety of molecular masses ranging from several to over 50 kilodaltons. Some of them possess different protease specificity and inhibitory constants toward proteases. They play a role in various physiological processes such as reproduction, protection from viral infection, regulation of endogenous and exogenous (pathogen) proteases and anticoagulation activity. _____________________________________________________________________________________________________________

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تاریخ انتشار 2012